The preparation of I- 123 mIBG in-house using this technique is recommended.« less ![]() Imaging of neuroendocrine tumors in 300 patients following injection of I- 123 mIBG or 1-131 mIBG prepared from a method, the specificity and sensitivity both exceed 90%, correlating well with multiple studies reported in the literature. ![]() WR evaluated by MIBG scintigraphy 3 weeks after the onset of STEMI is a significant predictor of MACE in patients with STEMI, independent of LVEF. Higher specific activity result in higher uptake of radioiodinated MIBG in all volunteers in the heart (p 45%, WR was a predictor of MACE, pump failure death, cardiac death and progression of heart failure in patients with STEMI. To clarify the effect of specific activity on cardiac uptake of radioiodinated MIBG, the distribution and kinetics of no-carrier-added MIBG (> or = 7.4 TBq/mumol) were compared with those of commercial MIBG (approximately 74 MBq/mumol) in three healthy volunteers by serial imaging and blood sampling. Recent in vivo studies predict enhanced cardiac uptake of this radiopharmaceutical with high specific activity. ![]() Radioiodinated meta-iodobenzylguanidine ( MIBG), an analog of norepinephrine, has been used to assess myocardial sympathetic innervation. Effect of specific activity on cardiac uptake of iodine- 123- MIBG.įarahati, J Bier, D Scheubeck, M Lassmann, M Schelper, L F Grelle, I Hanscheid, H Biko, J Graefe, K H Reiners, C
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